From transfer windows to high-efficiency air vents: 5 key points in building a three-tier protection system

Cleanroom environment management depends on building three-tier protection systems that function as the primary defense against space contamination and cross-contamination. Each protective step uplifts in importance within demanding settings like Operating Theatres starting from Pass Boxes through to HEPA Boxes.

1. The first level of protection: precise control of material transfer.

The first step of Cleanroom environment management involves material transfers through Pass Box as the fundamental connecting system between clean spaces and non-clean areas that blocks contaminant entry during transfers. Regular testing of the two-way transfer window with built-in UV sterilization features should become part of the maintenance plan to achieve safe material handling operations.

2. Second level of protection: high efficiency filtration for air purification

Air filtering stands as the foundation of three-level protection because the HEPA Box device supplies high-efficiency air with more than 99.97% efficiency at filtering 0.3 micron particles to maintain clean air quality. The Operating Theatre uses the HEPA Box together with laminar flow systems to create steady unidirectional airflow which decreases the likelihood of surgical infections.

3. Third level of protection: scientific design of cleanroom differential pressure

Cleanroom pressure difference establishes a vital defense system against contamination spread. The design of positive or negative pressure environments operates as a system which maintains airflow flow patterns through different cleanliness zones. Operating rooms should use gradient differential pressure systems with monitoring systems to dynamically adjust their differential pressure values.

4. Fourth level of protection: strict management of personnel and equipment

Clean environment contamination mainly comes from personnel and equipment. The Operating Theatre requires healthcare personnel to pass through rigorous regulations regarding changes of clothing and handwashing and air-showering routines and regular equipment sanitization. Buffer rooms should be added to critical areas through installation as an additional method to decrease personnel-induced contamination risks.

5. Fifth level of protection: environmental monitoring and continuous improvement

Environmental monitoring serves as the protective barrier against contamination in the three-level protection procedure. A system of real-time monitoring for suspended particles combined with microbial settlement bacteria and different indicator measurements allows for prompt detection of potential problems. Regular maintenance combined with verification procedures checks the long-term operational stability of the Pass Box and HEPA Box as well as other equipment.